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Fluorescence News
SBI, Theragnostics Agreement Will Accelerate Fluorescence-Based Oral Cancer Diagnoses
NEW YORK, Sept. 30, 2020 — An agreement signed this month is poised to broaden the scope and application of fluorescence-labeled poly ADP-ribose polymerase (PARP) inhibitors in cancer detection and diagnostics. Summit Biomedical Imaging (SBI), a clinical stage developer of diagnostic medical imaging products, reached a global license agreement for intellectual property with medical imaging and biotechnology company Theragnostics. The agreement contributes to SBI’s global freedom to operate in the diagnostic field
Single Microendoscope Acquires Photoacoustic, Fluorescent Images
GRENOBLE, France, Sept. 28, 2020 — An endoscope that combines photoacoustic and fluorescence imaging and that is about as thick as a human hair could one day provide insight into the brain by enabling the simultaneous measurement of blood dynamics and neuronal activity. The...
Bruker Acquires Canopy Biosciences
BILLERICA, Mass., Sept. 25, 2020 — Bruker Corp. has acquired Canopy Biosciences, a specialist in high multiplex biomarker imaging for immunology, immune-oncology, and cell therapy. The acquisition expands Bruker’s offerings in targeted multiomics and fluorescence-based imaging...
‘Firefly’ Imaging Technique Sheds Light on Molecular Forces
ATLANTA, Sept. 24, 2020 — Using tools made of luminescent DNA, researchers at Emory University have visualized the mechanical forces of cells at the molecular level. The researchers demonstrated the technique on human blood platelets. “Normally, an optical microscope...
Superresolution Microscopy Analysis Accelerated by Machine Learning
Sep 4, 2020 — Superresolution optical microscopy — a technology that enables the acquisition of fluorescent micrographs of samples with a resolution well below the optical diffraction limit of ~250 nm — is rapidly evolving. Several methods have been developed...
Imaging Method Enables Research on Abundant Cellular Protein Actin
LA JOLLA, Calif., Aug. 11, 2020 — Researchers at the Salk Institute have developed a new imaging method that allows them to monitor actin, a small subset of skeleton-like filaments within cells. The method has enabled research on how actin mediates an important function: helping...
Microscopy Methods Combined to Achieve Molecular Resolution
WÜRZBURG, Germany, July 13, 2020 — An international team of researchers has combined superresolution microscopy method dSTORM with expansion microscopy to overcome a previous limitation of superresolution microscopy. Previously, nanometer resolution had only been a theoretical...
Smartphone sensors could detect COVID-19
Jun 9, 2020 — Widely available and accurate testing will be an important tool for identifying those needing treatment and for controlling the COVID-19 pandemic. Testing is required to answer two important questions: 1) Am I infected? and 2) Do I have immunity?...
Olympus Announces Light Microscopy Image Awards
WALTHAM, Mass., March 27, 2020 — Olympus has announced the winners of its first Global Image of the Year Life Science Microscopy Award. The winning image, captured by Ainara Pintor of Spain using a superresolution confocal microscope system. The image shows the immunostaining of a...
Virus Testing Kits to Be Developed Using RNA Imaging Technology
BURNABY, British Columbia, March 20, 2020 — A Simon Fraser University (SFU) research team will be using RNA imaging technology it has created to develop coronavirus testing kits. The decision to apply the technology, called Mango, to COVID-19 testing is in response to a funding opportunity...
Imaging Agent Illuminates Cancer and Surrounding ‘Hijacked’ Cells
ST. LOUIS, March 18, 2020 — Scientists at Washington University School of Medicine have developed an imaging agent that can identify multiple types of tumors as well as the surrounding normal cells that the cancer uses as a shield against attempts to destroy it. “This...
Optomagnetic Technology Could Reduce Coronavirus Diagnostic Time
RAMAT GAN, Israel, March 16, 2020 — A technology developed at Bar-Ilan University, based on a combination of optics and magnetic particles, can rapidly test samples of patients potentially infected with the coronavirus. Current methods for diagnosing coronavirus take approximately one...
Spectroscopic Toolkit for Structural Biology Could Aid in Drug Design
CLEMSON, S.C., March 10, 2020 — A fluorescence-based imaging technique for monitoring single molecules could lead to a better understanding of how molecules are assembled, function, and interact, aiding in structure-guided drug design. Clemson University researchers led by...
Fluorescent Imaging Helps Identify Lung Cancer Lesions During Surgery
PITTSBURGH, Feb. 24, 2020 — A tumor-highlighting technology called OTL38 enhances the visualization of lung cancer tissue through near-infrared imaging, providing surgeons with a significantly better chance of finding and removing more cancer than previously possible. The...
Electric Fields Affect Molecular Twist Within Light-Sensitive Proteins
MENLO PARK, Calif., Feb. 18, 2020 — A team of scientists from the Department of Energy’s SLAC National Accelerator Laboratory and Stanford University has gained insight into how electric fields affect the way energy from light drives molecular motion and transformation in a...
Marriage of Microscopy Techniques Reveals Cells’ 3D Ultrastructure
CHEVY CHASE, Md., Jan. 21, 2020 — Scientists at the Howard Hughes Medical Institute (HHMI) have combined superresolution fluorescence microscopy and electron microscopy to shed new light on the structures and organizations within cells. Superresolution fluorescence microscopy on its...
Ghost Imaging Speeds Up Superresolution Microscopy
SHANGHAI, Jan. 6, 2020 — Scientists from the Chinese Academy of Sciences have developed a new imaging technique that produces nm-scale resolution using significantly fewer images than traditional nanoscopy techniques. The scientists used ghost imaging to enhance the imaging...
Fluorescent Dye Helps Detect Reactive Oxygen Species
BATH, England, Dec. 27, 2019 — Scientists at the University of Bath have developed a fluorescent tool for detecting reactive oxygen species based on a chemical found in mushrooms. Reactive oxygen species (ROS), such as free radicals and peroxides, are produced in cells under...
Researchers Find Way to Supercharge Protein Production
ST. LOUIS, Dec. 27, 2019 — Even though scientists have engineered bacteria to make therapeutic proteins, medicines based on these proteins, such as insulin and clotting factors for hemophilia, are still difficult to synthesize in the lab. Now, through the use of green...
Fluorescence Microscopy: Getting the Picture Right
Sep 18, 2019 — Fluorescence microscopy is a very broadly used term covering numerous applications. It ranges from basic life science applications such as time-lapse cell viability assays — in which dead cells are counted as they start to fluoresce by intrusion of...
Single-Molecule Localization Microscopy Approach Improves Precision
BEIJING, Sept. 17, 2019 — An interferometric, single-molecule localization method for superresolution fluorescence microscopy, developed by scientists at the Institute of Biophysics of the Chinese Academy of Sciences, could significantly improve localization precision...
Superresolution Imaging Method Aids in Water Decontamination
ITHACA, N.Y., July 10, 2019 — An imaging technique developed by Cornell University researchers shows promise as a tool for decontaminating water. The new approach allows imaging of catalytic reactions at the nanoscale in real time to help researchers learn the optimal size and...
Antibody-based Probe Developed for Live-Cell Imaging in Vivo
FORT COLLINS, Colo., July 5, 2019 — To expand the toolbox of imaging in living cells, researchers from Colorado State University and the Tokyo Institute of Technology have developed a genetically encoded, antibody-based probe that works with specificity in vivo. In this methodology,...
Innovations in Flow Cytometry Expand Its Use in Clinical Diagnostics
Jun 12, 2019 — The outstanding achievements of immunologists James P. Allison and Tasuku Honjo — winners of the 2018 Nobel Prize for medicine for their discovery of cancer therapy by inhibition of negative immune regulation — are at the forefront of an...
LOTUS-V Brain Imaging Technique Shows Promise In Neuroscience
OSAKA, Japan, June 7, 2019 — Researchers at Osaka University have developed a method to record brain activity in multiple freely moving mice simultaneously. The method is based on a recent bioluminescence-based indicator of membrane voltage. Researchers applied the indicator...
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May/Jun 2024
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