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Fluorescence News
Active Illumination Microscopy for Live-Cell Imaging
Nov 1, 2010 — Photobleaching and phototoxicity are unavoidable in fluorescence microscopy. The phenomenon of photobleaching occurs when, as a result of photo-induced modifications to the molecular structure, a fluorophore permanently loses the ability to fluoresce. Phototoxicity arises from photoinduced generation of singlet oxygen and/or other toxic by-products. Both phenomena are detrimental to fluorescence microscopy applications, especially in the case of live-cell imaging, where real-time effects c...
Lantos Technologies Inc.
Nov 1, 2010 — In Massachusetts, Lantos Technologies Inc. of Cambridge has announced that it has closed on a $1.6 million deal to develop its 3-D ear canal imaging technology. Braintree-based Catalyst Health Ventures led the round, which was joined by Boston-based...
Sterilizing with Fluorescent Light
WASHINGTON, Oct. 28, 2010 — The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) infections is well-known, causing an estimated 19,000 deaths yearly in the US and $3 billion to $4 billion in health care costs. What is less well-known is that this increased...
Combining Second-Harmonic Generation with Multiphoton Imaging
Oct 1, 2010 — Second-harmonic generation (SHG) is a method of imaging structures in tissue using a pulsed near-infrared laser. The technique can be combined with various methods of fluorescence imaging to deduce molecular organization and other key aspects of...
Your Prion Eyes
Oct 1, 2010 — When you gaze into someone’s eyes, you can tell much about their character. It just so happens that you also might be able to tell whether they have a neurological disease. Jacob W. Petrich and his colleagues at Iowa State University in Ames...
Laser Components, PicoQuant to Develop Photon Counters
OLCHING, Germany, Sept. 16, 2010 — Laser and optoelectronic components and services manufacturer Laser Components GmbH announced it has forged a strategic alliance with PicoQuant GmbH of Berlin, to develop and commercialize photon counters. Working together, Laser Components DG...
Standardized Units for Reproducible Imaging Experiments
Sep 1, 2010 — Discerning why experimental results sometimes differ is problematic for researchers because current scientific cameras report data in nonstandardized ways, prohibiting direct and quantitative comparisons between experiments. “People in my lab...
Omega Optical, Spectral Molecular Win SBIR Award
BRATTLEBORO, Vt., Aug. 18, 2010 — Omega Optical Inc. announced it has won a Phase II Small Business Innovation Research award from the National Cancer Institute to develop a high-speed fiber optic-based optical spectrum analyzer (OSA) that will be interfaced to confocal scanning...
PerkinElmer Acquires VisEn
WALTHAM, Mass., Aug. 4, 2010 — PerkinElmer Inc. announced it has acquired VisEn Medical Inc. of Bedford, Mass., an in vivo molecular imaging technology company. The acquisition has enabled the company that focuses on the health and safety of people and the environment to enhance...
Is Vibration Control Really Necessary for Microscopy?
Jul 1, 2010 — As a supplier of vibration control equipment, we at Newport are frequently asked if vibration control is really necessary for microscopy applications, and you might expect the answer to be “of course.” However, the correct response is...
Strathclyde Institute of Pharmacy and Biomedical Sciences
Jul 1, 2010 — At the Centre for Biophotonics of the Strathclyde Institute of Pharmacy and Biomedical Sciences, a new microscope has been built that could provide breakthroughs for cancer treatment and drug discovery. The microscope uses a less complex laser...
Medicine and the life sciences add fiber
May 17, 2010 — Compact, reliable, powerful and efficient, fiber lasers are being put to use in medicine and the life sciences, where one device can replace a half dozen or so other lasers or can enable higher-resolution imaging, thereby offering new capabilities....
New Approaches to Traditional Fluorescence Illumination
May 17, 2010 — Fluorescence microscopy presents an array of illumination challenges. Key among these is matching the spectrum of the light source to the fluorophore in the sample, to the bulb alignment and lifetime, and to the evenness of illumination. A new lamp...
Lab Chips Get Specific
Apr 12, 2010 — After sometimes seeming like a solution in search of a problem, lab-on-a-chip technology may be finding its footing in application-specific incarnations, not in general-purpose devices. One key to its success is finding the right targets and better...
Qiagen NV
Mar 24, 2010 — Sample and assay technologies provider Qiagen NV of Venlo, the Netherlands, has purchased ESE of Stockach, Germany, an ultraviolet and fluorescence sensor technology company, for $19 million in cash. ESE’s development and manufacturing site will be...
VisEn Medical Inc.
Mar 24, 2010 — Fluorescence in vivo imaging provider VisEn Medical Inc. of Bedford, Mass., has announced that it has acquired the fluorescence imaging agent intellectual property portfolios and related technology platforms of Bayer Schering Pharma AG of Berlin....
Autoprobing Tech for Fast Diagnoses
SANKT AUGUSTIN, Germany, March 22, 2010 — The Fraunhofer Institute for Applied Information Technology (FIT) has developed a fully automated high-performance microscope with which researchers will be able to study the complex interactions of proteins between cells.
Funding riskier research
Feb 28, 2010 — For the greatest reward, you sometimes have to take the most risk. Even though balancing risk against reward can be difficult, the federal government does it all the time in fundin...
High-throughput screening with photonic crystal biosensors
URBANA, Ill. – Identifying small molecules that inhibit or enhance protein-protein interactions is an important part of the drug discovery process. Being able to screen through large libraries of molecules to find those with the strongest ability to do so is...
Learning how neurons talk to each other
CAMBRIDGE, Mass. – In the past, scientists could study only one neuron at a time in the nematode Caenorhabditis elegans. Now they can look at how tens of neurons in the roundworm interact with one another in vivo. This nematode, with a total of just 302 neurons, is a...
Li-Cor Biosciences
Feb 28, 2010 — Li-Cor Biosciences of Lincoln, Neb., and Spectros Corp. of Portola Valley, Calif., have announced a nonexclusive licensing and supply agreement to couple the former company’s IRDye 800CW to the latter’s targeted biomarkers. Additionally, the...
PW10: Variety at Edmund Optics
SAN FRANCISCO, Jan. 29, 2010 – Flexibility was a recurring theme among exhibitors at SPIE Photonics West this year, and Edmund Optics (EO) was no exception: The Barrington, N.J.-based company had a large number of new and recent products on display, including hands-on...
Applying logic yields intelligent diagnostics
MEDFORD, Mass. – By applying molecular logic, researchers at Tufts University have demonstrated what could be the foundation for intelligent medical diagnostics. Their fluorescence-based approach c...
Oclaro Offers Lifetime Warranties
SAN JOSE, Calif., Jan. 21, 2010 – Oclaro Inc., an optical components provider for industrial applications, has announced it will provide lifetime warranties for its line of Clarity fluorescence filters used in biom...
Using selectivity and sensitivity to detect the whole tumor
SAN DIEGO – Removing tumors and detecting even the most slightly diseased tissue have become easier with the help of bright GFP and a GFP-expressing adenovirus. The fluorescence labeling technique, described in a recent study, will help to target and illuminate...
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May/Jun 2024
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