Broad Palette of Fluorescent Dyes May Advance Biological Imaging
ASHBURN, Va., Oct. 19, 2017 — To better illuminate the inner workings of cells, researchers have developed a way to adjust the properties of fluorescent dyes deliberately, resulting in an expanded palette of dyes that are bolder, brighter and more cell-permeable. Their novel technique could allow chemists to synthesize dyes in hundreds of different colors. For this work, researchers at Howard Hughes Medical Institute (HHMI) focused on rhodamines, a family of fluorescent dyes that are especially bright and