Advancing Raman Spectroscopy by Using Bioresponsive Optical Nanomaterials
Tue, Jul 8, 2025 1:00 PM - 2:00 PM EDT
Raman spectroscopy provides label-free molecular characterization by detecting chemical bond vibrations, enabling direct visualization of molecular responses in living cells and tissues. Despite significant advancements, the clinical translation of Raman spectroscopy has been hindered by two key challenges: limited detection sensitivity and insufficient specificity. For instance, it has not found use in imaging enzyme activity, a significant aspect of biomedical research.Leveraging nature-inspired self-assembly strategies, intracellular bioorthogonal enzyme-responsive nanoprobes (nanoSABER) have been developed. Engineered from enzyme-responsive peptides, these nanoprobes assemble into supramolecular structures with distinct Raman-active vibrational signatures upon interaction with targeted enzymes. Incorporating vibrational tags such as alkyne (C=C) and nitrile (C=N) groups within the cell-silent Raman window (1800 to 2600 cm-¹), nanoSABER specifically images enzyme activity with minimal interference from endogenous cellular signals. Sponsored by DialAct Corporation and OceanOptics.
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Optimization of LED Illumination for Hyperspectral Imaging Applications
Wed, Jul 9, 2025 11:00 AM - 12:00 PM EDT
This webinar introduces key principles of inline hyperspectral imaging and focuses on the often-overlooked design and integration of illumination. Attendees will learn how to optimize system throughput, sensitivity, and spectral accuracy by properly matching illumination performance to the capabilities of their spectral imaging cameras. We will compare traditional broadband sources, such as tungsten-halogen lamps, to modern solid-state LED systems—evaluating factors such as spectral coverage, uniformity, angular distribution, thermal stability, and cooling techniques. Whether you are developing new HSI camera systems or integrating spectral imaging into existing automation platforms, this webinar will offer practical insight into achieving better results through optimized, application-specific illumination strategies. Hyperspectral imaging (HSI) is revolutionizing industries like food processing, materials recycling, and pharmaceuticals by enabling high-speed, non-contact identification of product characteristics. Yet, one of the most underestimated—and absolutely critical—determinants of overall system performance is the illuminator. This webinar will reveal how optimized, performance-driven LED illumination strategies can dramatically improve results, unlock new capabilities, and give your solutions a competitive edge in the marketplace. Presented by Innovation In Optics, Inc.
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Quantum Sensing with Atomic Systems and Reconfigurable Instrumentation
Wed, Jul 23, 2025 1:00 PM - 2:00 PM EDT
Quantum sensing leverages the fundamental quantum behavior of atoms and light to measure weak signals with precision beyond that of classical methods. These measurements make use of trapped ions and cold atoms, and include applications such as magnetic field sensing, optical atomic clocks, and quantum gravimetry. Critical to these techniques are ultra-cold temperatures, coherent quantum control, and sensitive optical readout, which pose significant hardware challenges with regard to laser stabilization, timing, and noise suppression. During this presentation, find out how to generate and detect synchronized RF pulse trains, such as a Ramsey sequence, using a software-defined waveform generator and lock-in amplifier. Plus, see new ways to stabilize your systems with a laser lock box and measure clock stability with a phasemeter, using a reconfigurable suite of instruments in a single device. Finally, in a live demonstration, learn how to deploy these instruments simultaneously for maximum flexibility, and how to use Python to interface with each. Presented by Liquid Instruments.
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Call for Articles
Photonics Media is currently seeking technical feature articles on a variety of topics for publication in our magazines (Photonics Spectra, BioPhotonics, and Vision Spectra). Please submit an informal 100-word
abstract to editorial@Photonics.com, or use our online submission form.
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