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BioPhotonics Monthly: Microscopy, Light-Sheet Microscopy, Quantum Dots, and more. (8/26/2020)

BioPhotonics Monthly: Microscopy, Light-Sheet Microscopy, Quantum Dots, and more.

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Wednesday, August 26, 2020

Monthly newsletter focusing on how light-based technologies are being used in the life sciences. Includes news, features and product developments in lasers, imaging, optics, spectroscopy, microscopy, lighting and more. Manage your Photonics Media membership at Photonics.com/subscribe.

Quantum Dots Put Focus on Neuronal Imaging
Despite increasing efforts to solve the puzzle that is the workings of the human brain, scientists’ current understanding of the brain’s functional interconnections remains limited. As the most complex organ in the human body, the brain is an immense network of neuronal cells capable of sending signals to receptors in the rest of the body. These signals begin as chemical changes, such as rapid variations in ion concentration through sodium and potassium (Na+/K+) ion channels in the neuronal cell membranes, which in turn result in electrical potential changes across the plasma membrane.

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Microscopic Methods Reveal Holistic Picture of Sample
Whole slide imaging is a method principally employed when scientists need to image a large, relatively two-dimensional sample that expands beyond a single microscope field of view. Typical applications include imaging of histological tissues that have been cut into thin slices and placed on a glass slide.

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Lattice Light-Sheet Microscopy Tool Supports 4D Data Analysis
Researchers at the University of Chicago have designed a multidimensional imaging analysis pipeline for lattice light-sheet microscopy. They set out to study T-cell function using high-dimensional microscopy, but then identified the need for an effective method of analysis.

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.: Featured Products

Bring Your Product to Life

Optikos Corporation
Have a project in mind? Work with our talented team of engineers to bring your next idea to life. From concept and design to prototype and production, you can do it all with Optikos.

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Optics and Illumination Software

Lambda Research Corp.
TracePro combines a graphical user interface with solid modeling, Monte Carlo ray tracing, analysis features, CAD import/export, optimization methods, and a complete and robust macro language to solve a wide variety of problems in illumination design and optical analysis.

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CELESTA Light Engine

Lumencor Inc.
Lumencor’s CELESTA Light Engine delivers exceptional brightness and speed. This laser-based, solid-state illuminator is designed to support today’s most demanding multidimensional fluorescence microscopy applications.

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Light Sheet for Cleared Tissue

Applied Scientific Instrumentation Inc.
A flexible and easy-to-use SPIM configuration optimized to image large cleared samples. The sample is mounted horizontally on an XYZ stage. Two multi-immersion objective lenses are held in an upright “V” geometry for light sheet illumination and detection.

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.: In Case You Missed It

Light Helps Pump Life into Heart Muscle
Although it can be difficult to get heart muscle cells to propagate in large numbers, a team of researchers at the University of Minnesota has found a way to use 3D printing and light-induced excitation to create a living heart pump that has broad implications in medicine.

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Tunable Laser Determines Best UV Wavelengths for Germ Eradication
While awaiting full access to their labs due to COVID-19 restrictions, scientists at the National Institute of Standards and Technology (NIST) have taken the time to report on research conducted in 2012 on the disinfection of drinking water using ultraviolet (UV) light. The research was published online in July 2020 by the Review of Scientific Instruments.

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Flickering Light Mobilizes Brain Chemistry That May Fight Alzheimer’s
Previous experiments using flickering light to treat neurodegenerative disease have shown promise, and now, researchers at the Georgia Institute of Technology (Georgia Tech) may have discovered how the flicker works. They found that exposure to light pulsing at 40 hertz (Hz) — 40 beats per second — caused the brains of healthy mice to release a surge of signaling chemicals that could help fight Alzheimer’s disease.

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.: Upcoming Webinars

LED Lighting for Fluorescence Microscopy: A Sustainable Illumination Option
Tue, Sep 22, 2020 10:00 AM - 11:00 AM EDT
This webinar, presented by Excelitas Technologies, will present the recent advancements in LED technology that have created an opportunity for LEDs to replace arc lamps for a variety of fluorescence imaging applications. Presenter Kavita Aswani, Ph.D., will address the development of high-power LEDs for the green excitation range, a wavelength that has traditionally been challenging for LEDs. She will also discuss the many advantages of using LEDs for microscopy systems in life sciences, including sustainability.

.:Next Issue:

Features
Biothermophotonics, Hand-Held Microcopy, Vibrational Spectroscopy, and more.

Photonics Media is currently seeking technical feature articles on a variety of topics for publication in our magazine BioPhotonics. Please submit an informal 100-word abstract to Senior Editor Doug Farmer at [email protected], or use our online submission form www.photonics.com/submitfeature.aspx.

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