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Wednesday, October 25, 2017
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Monthly newsletter focusing on how light-based technologies are being used in the life sciences. Includes news, features and product developments in lasers, imaging, optics, spectroscopy, microscopy, lighting and more. Manage your Photonics Media membership at Photonics.com/subscribe.
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sponsor
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Single-Molecule Localization Blazes New Paths for Microscopy
Fluorescence microscopy has proven itself to be an indispensable method in the modern biological toolkit. The use of visible-wavelength fluorophores allows for relatively noninvasive imaging. While the resolution of conventional optical microscopy cannot rival that of electron, atomic force or near-field scanning optical microscopy methods, the unrivaled specificity of the technique allows for the imaging of nearly any biological target.
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3D Mapping of Neural Circuits In Vivo Opens the Window on Neurological Disease
Despite extensive research, brain function and neurological diseases are poorly understood. Complexities arise from the quantity of neurons in the brain and from the densely interconnected networks of intermixed cell types. Tools neuroscientists have traditionally relied upon include the patch clamp, which probes electrical activity of a single neuron, and fMRI, which images activity in volumes containing millions of neurons.
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Forensic Microscopy Expands Its Reach
The field of forensic microscopy is more than a century old. Though practitioners say their profession is far less glamorous than its portrayal in popular TV crime and courtroom shows, forensic investigation remains a powerful tool for learning the truth about who may have committed various actions, where they occurred, and what tools or substances may have been used.
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Light Sheet Microscopy (oSPIM)
Applied Scientific Instrumentation Inc.
ASI’s Oblique Single Illumination Microscope (oSPIM) is an excellent platform for high resolution light sheet microscopy for samples mounted in standard coverslip-bottom culture dishes. The oSPIM is a single-view light sheet system where the illumination light sheet is generated at an oblique angle using an oil immersion objective below the sample dish.
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A miniaturized hyperspectral device has been developed as an add-on for a standard camera and could be used to repurpose a camera for generating hyperspectral images and videos for a range of applications.
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A team of scientists has successfully developed the Swept Confocally Aligned Planar Excitation (SCAPE) 3D microscope, which eliminates the need to mount samples or other special preparation and is capable of imaging freely moving living samples in real-time at speeds 10 to 100 times faster than current laser-scanning microscopes.
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Making Laser-Based Dermatologic Procedures Safer and More Effective
Thu, Nov 2, 2017 1:00 PM - 2:00 PM EDT
This webinar will introduce sonoillumination, a technique that uses ultrasound in conjunction with a clinical laser for dermatologic procedures such as the removal of birthmarks and tattoos. Sonoillumination transmits laser light only through direct contact with the skin, maintaining a safe environment for physician and patient throughout treatment. The ultrasound is applied throughout the procedure to further improve effectiveness by increasing the transmission of light through the epidermis by as much as 174 percent. The presenters will review current approaches to laser-based dermatological treatments, then will discuss sonoillumination, the experimental methods used to test the device, and results.
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Features
3D Medical Imaging; IIR Medical Imaging; Tunable Lasers; Cameras for Microscopy
Issue Bonus
Annual Imaging Sourcebook: Research, Market Report, Directory
Photonics Media is currently seeking technical feature articles on a variety of topics for publication in our magazine BioPhotonics. Please submit an informal 100-word abstract to Associate Managing Editor Marcia Stamell at [email protected] or use our online submission form www.photonics.com/submitfeature.aspx.
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