< More BioPhotonics NewsletterSubscribe to our E-NewslettersBioPhotonics Newsletter — Optical Photothermal IR Spectroscopy, Holography in Neuroscience, and more… (1/25/2023)
BioPhotonics Newsletter — Optical Photothermal IR Spectroscopy, Holography in Neuroscience, and more…
Monthly newsletter focusing on how light-based technologies are being used in the life sciences. Includes news, features and product developments in lasers, imaging, optics, spectroscopy, microscopy,
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Wednesday, January 25, 2023 |
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Monthly newsletter focusing on how light-based technologies are being used in the life sciences. Includes news, features and product developments in lasers, imaging, optics, spectroscopy, microscopy, lighting and more. Manage your Photonics
Media membership at Photonics.com/subscribe.
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Optical Photothermal IR Spectroscopy Targets Single-Cell Metabolomics
Due to its unique molecular fingerprinting capability, infrared spectroscopy has been widely used to interrogate the overall biochemistry of biological systems. Over the years, this capability has proved the technique’s worth as a powerful physicochemical method with broad applications within the life sciences. A novel far-field pump-and-probe technique called optical photothermal infrared (O-PTIR) spectroscopy has recently been developed to acquire infrared chemical images from samples quickly. The technique’s impacts and limitations, as well as its future potential in biomedical research, can be projected, along with its potential applications as a tool for single-cell microbial metabolomics and for studying tissue diseases.
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Advanced Holography Efficiently Illuminates Neuronal Patterns
Demystifying the complexity of the human brain is one of the last frontiers in diagnostics and therapeutics. When the brain is sufficiently understood by clinicians, the benefits for human well-being — in the form of cures and treatments for neurodegenerative diseases — will be profound. Such knowledge, gained by using sophisticated illumination patterns in conjunction with artificial intelligence and advanced algorithms, could forever change the way that medical treatment for many conditions is dispensed.
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Fluorophore Modified to Expand Monitoring of Cell Dynamics
A genetically modified fluorescent protein has exhibited the shortest fluorescence emission wavelength to date, researchers at Osaka University reported. The fluorophore, named Sumire, emits 414-nm violet fluorescence from a hydrated chromophore. The development of Sumire will make it possible for scientists to track a larger number of biomolecules at the same time, increasing their ability to simultaneously monitor a cell’s many dynamic processes.
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.: Featured Products & Services
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LS850 Fully Automated Microscope
Etaluma Inc.
The LS850 Microscope is the latest generation of our fully automated three-channel flagship model and offers the latest advances in optics, cameras, throughput, and user flexibility delivering image quality, motion speed, illumination, and software flexibility.
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Single-Objective Light Sheet
Applied Scientific Instrumentation Inc.
Based on the OPM and SCAPE technologies and developed in collaboration with Leica Microsystems, microscope enables fast and gentle volumetric imaging of fluorescent biological samples over many time points and multiple channels, all while using conventional sample mounting.
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Custom Fiber Optic Solutions
Armadillo SIA
Armadillo SIA offers a comprehensive line of optical fibers, cables, bifurcated assemblies, patch cords, bundles, and more — all custom designed to your specifications. Assemblies can be made from any of our high-quality fibers and your choice of sheathing, cabling, and jacketing. In addition, we offer all standard connectors or custom-designed ferrules to suit applications from deep UV to MIR.
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Bring Your Next Product to Market
Optikos Corporation
Optikos engineering services will help bring your next medical device or diagnostic product from design to market. Optics makes amazing things possible in life sciences, and Optikos makes it happen.
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Acoustic Imaging Aims to Reduce Tissue Damage from Radiation Therapy
The need to deliver the intended, optimal radiation dose to a tumor while sparing the healthy tissue surrounding the cancer is critical to cancer treatments using radiation therapy. Now, with a real-time, 3D imaging system developed at the University of Michigan, doctors and other medical professionals may be able to direct radiation with more precision, limiting the exposure of adjacent tissue.
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Hydrogel Improvements Expand Utility of Expansion Microscopy
Collaborators from Carnegie Mellon University, the University of Pittsburgh, and Brown University have described a microscopy technique and set of protocols that overcome a bottleneck to the expansion microscopy method. The collaborators developed “Magnify” as a variant of expansion microscopy that uses a hydrogel that retains a spectrum of biomolecules, offers a broader application to a variety of tissues, and increases the expansion up to 11× times linearly or approximately 1300 folds of the original volume.
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Laser-Induced Protein Detection Speeds Disease Diagnosis
Researchers at Osaka Metropolitan University have developed an optical alternative to immunoassays and other methods used for protein analysis. The alternative method provides rapid, highly sensitive detection of proteins through laser irradiation.
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Quantitative Stimulated Raman Scattering Microscopy: From Molecules to Animals
Tue, Feb 14, 2023 1:00 PM - 2:00 PM EST
Dan Fu, Ph.D., from the University of Washington highlights the capability of stimulated Raman scattering (SRS) microscopy in imaging various molecules in heterogenous samples from simple mixtures to living cells and animals. He then shares the challenges in quantitative analysis with SRS imaging due to scattering, as well as potential solutions in leveraging water as an internal standard. With continuous improvement in imaging resolution, sensitivity, and specificity, SRS is poised to play an important role in biomedical imaging.
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Features
Photoacoustic Microscopy, Raman Spectroscopy, Dynamic Light Scattering & Alzheimer’s, Aptamer Molecular Photonic Beacons
Photonics Media is currently seeking technical feature articles on a variety of topics for publication in our magazine BioPhotonics. Please submit an informal 100-word abstract to Senior Editor Doug Farmer at [email protected], or use our online submission form www.photonics.com/submitfeature.aspx.
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About BioPhotonics
BioPhotonics is the global resource for research, business and product news and information for the biophotonics community and the industry's only stand-alone print and digital magazine.
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