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BioPhotonics - October 2018
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Issue Library
Digital Edition
Features
Smartphone Spectroscopy Takes the Lab to the People
By 2020, the number of smartphone users in the world is expected to reach almost 2.9 billion — nearly doubling in six years from about 1.6 billion in 2014. Technology companies and researchers have been directly and indirectly imbuing smartphones with additional capabilities, including spectroscopy for biological and medical applications, among other uses (Figure 1). Figure 1. The Changhong...
Neuroscience 2018 Encourages Collaboration
Developments in cell biology are uncovering new methods with which to study synaptic communication, social behavior circuits, and healthy and diseased brains. Advanced study and understanding of...
Miniaturization, Increased Resolution Drive Microscopy’s Future
Miniature fluorescence microscopes and other system components, such as liquid lenses, are among emerging microscopy advancements that are bettering optical inspection in areas including the life...
SHG Microscopy Brings Live Cells into 3D Focus
Second-harmonic generation (SHG) microscopy brings the imaging of select biomolecular assemblies into 3D focus. It highlights biomolecules that follow specific structural organization within...
Nanophotonic Biosensors Expand Live Cell Analysis
In an era of fast-emerging personalized therapies, accuracy and efficacy rely mainly on precise cell analysis and engineering. With advanced gene sequencing technologies, researchers have revealed...
Editorial
Nanobiosensors Boost Live Cell Study, Understanding
The inner workings of the human body are complicated, with a comprehensive view of issues such as infection, cancer cells, viruses, and others sometimes difficult to obtain. In spite of such complexity, researchers and clinicians must have a clear understanding of the body’s mechanisms and live cells to ensure the most accurate medical diagnoses, and thus provide patients the most effective...
BioScan
Hand-Held Imager Could Broaden Use of AOSLO
Researchers at Duke University have miniaturized adaptive optics (AO) technology to develop a portable hand-held ophthalmology device that can image individual photoreceptors in the eye at high resolution. The new instrument could allow improved diagnosis of eye diseases to a larger population and enable early detection of brain-related diseases and trauma. To image photoreceptors, doctors...
Biosensor Monitors Oxygen in Organ-on-a-Chip Systems
A new photonic biosensor can track oxygen levels in real time in organs-on-a-chip to ensure that these systems are mimicking the function of physical organs. Developed at North Carolina State...
Nanoplasmonics Enables Label-Free Measurement of Bacteria Formation
Using nanochip technology and a targeted beam of light, scientists have devised a real-time, label-free way to monitor biofilms, an important component in the search for alternatives to...
Device Built via Laser Lift-Off Could Advance Precision Medicine
Researchers have fabricated a flexible drug delivery microdevice (f-DDM) with controlled release using a laser micromachining technique. The device could provide controlled release for personalized...
Low-Level Light Therapy Alleviates,Treats Digital Ulcers
A lamp containing 32 bulbs emitting IR, red, or UV light for use in low-level light therapy (LLLT) was tested on finger ulcers caused by an autoimmune condition. Researcher Michael Hughes, from the...
Photoacoustic Ultrasound Could Measure Periodontal Health
Researchers from University of California, San Diego used photoacoustic (optoacoustic) imaging with a contrast agent to measure pocket depths in swine models. The measurements were compared to those...
Purdue Developes 'Tornado' Lab-on-a-Chip with Nanotweezers
Purdue University researchers have developed a new class of optical nanotweezers that can rapidly trap and detect biomolecules, viruses, and DNA. The technology can also use light to detect cancer or...
Fluorescent Probe Identifies Cancer Stem Cells in the Body
A fluorescent probe, called AlDeSense, has demonstrated the ability to find and track cancer stem cells (CSCs) in cultures of multiple human cancer cell lines as well as in live mice. The new probe...
DIY Camera Tracking System Captures Plant Movement in Real Time
Farmers and plant breeders can now build their own automated field camera track system to collect data on dynamic plant traits, as changes occur. The do-it-yourself system can capture videos of plant...
LED Lights Reduce Bird Deaths from Fishing by 85 Percent
Researchers report that illuminating fishing nets with LED lights could reduce the number of seabirds that die from getting caught in nets by more than 85 percent. Fishing net with LED lights....
All-Optical Ultrasound System Provides Video-Rate, 2D Imaging
Researchers demonstrated the use of an all-optical ultrasound imager for video-rate, real-time 2D imaging of biological tissue. The achievement is an advance toward making all-optical ultrasound...
RapidScan
New HORIBA Facility Features Labs, Training Spaces
Instrumentation provider HORIBA Scientific celebrated the official opening of its new office facility in Piscataway, N.J. Official ribbon-cutting ceremony at HORIBA Scientific's new office complex in Piscataway, N.J. Courtesy of Justine Murphy. The opening ceremonies included several speeches highlighting HORIBA’s continued growth, as well as its commitment to the Garden State, and a ribbon...
MBI’s Fingerhut Receives 2018 ERC Starting Grant
Benjamin Fingerhut, junior group leader at the Max Born Institute (MBI), is recipient of the 2018 European Research Council (ERC) Starting Grant to address ultrafast biomolecular dynamics via a...
Oxide Acquires VUV Laser Business from Lumeras
Oxide Corp. has acquired the vacuum ultraviolet (VUV) laser business from Lumeras LLC. Lumeras produces high-photon-energy (11 eV, λ = 114 nm) laser sources used in research institutes...
Schott’s LuminaLine Wins Red Dot Design Award
Glass developer Schott AG’s LuminaLine Lighting Technology, a fiber lighting concept, has received the 2018 Red Dot: Best of the Best material design award. A jury of 40 internationally...
Ditzel, Wagenbauer Receive 2018 Nano Innovation Award
Two young researchers were awarded the 2018 Nano Innovation Award at the Center for NanoScience (CeNS) of the Ludwig-Maximilians-Universität (LMU) Munich for their master’s or doctoral thesis in...
BioTek Gets US Patent for Autofocus Reader, Software
Life science instrumentation developer BioTek Instruments Inc. was issued a patent by the U.S. Patent and Trademark Office for its User-Trained Autofocus feature in its Gen5 Microplate Reader and...
Science Exchange to Offer LI-COR Imaging Suite
Imaging systems developer LI-COR Biosciences is collaborating with Science Exchange, an outsourced R&D marketplace, to offer a suite of molecular imaging services based on LI-COR’s pioneer...
Gooch & Housego Acquires Integrated Technologies
Gooch & Housego (G&H) has completed the acquisition of Integrated Technologies Ltd. (ITL). ITL provides full product development, design, manufacturing, and after-sales service for the...
UC Riverside’s Professor Receives $750K DOE Grant for Organic-Inorganic Materials
Ming Lee Tang, an assistant professor of chemistry at the University of California, Riverside, has received a $750,000 grant from the U.S. Department of Energy (DOE) to continue her work on...
Stanford’s Gambhir Wins Cassen Prize
Dr. Sanjiv (Sam) Gambhir, known for his work in multimodality molecular imaging, was awarded the Benedict Cassen Prize at the 2018 Annual Meeting of the Society of Nuclear Medicine and Molecular...
Cardiovascular Systems, Aerolase Joins Forces
Cardiovascular Systems Inc. (CSI), a medical device company that develops and commercializes interventional treatment systems for patients with peripheral and coronary artery disease, has signed an...
Insight Medical, Onkos Surgical Team Up for Surgical Oncology AR
Medical device company Insight Medical Systems has teamed up with surgical oncology company Onkos Surgical Inc. to explore opportunities to apply Insight Medical’s Augmented Reality...
OmniGuide Inc. to Acquire Lisa Laser
OmniGuide Holdings Inc., a developer of patient-safety-focused advanced surgical energy tools, has announced an agreement to acquire Lisa Laser Products OHG, a surgical laser company based in...
Avinger Begins Study on OCT, IVUS for Treating PAD
Medical device developer Avinger Inc. has begun a study comparing optical coherence tomography (OCT) with intravascular ultrasound (IVUS) as imaging tools for diagnosing and treating peripheral...
Optogenetics Pioneer Receives Berthold Leibinger Zukunftspreis
For his groundbreaking work with lasers in the development and implementation of optogenetics, Karl Deisseroth will receive the Berthold Leibinger Zukunftspreis on September 21, 2018 in Ditzingen,...
BioOpinion
The R/evolutionary Divide
In countless R&D labs the world over, a pitched battle rages on, generally quietly, behind conference room doors and in presentations. The battle pits the evolutionaries against the revolutionaries. The evolutionaries argue that genius insight is overblown and that the ultimate value of innovation is lost without dotting the i’s and crossing the t’s. The revolutionaries, on the...
Postscripts
Photonics to Help Moo-ve the Dairy Industry Along
The milk supply chain generally starts on a dairy farm, where the milk moves from the cows to cooling storage tanks and then to tanker trucks that transport the milk to a dairy processor. There, it’s tested to ensure it was properly chilled and is free of bacteria. The milk is homogenized, pasteurized, packaged, and shipped. Getting that milk from dairy farm to store shelf is a complicated...
Products
Superresolution Microscope
The N-SIM S superresolution microscope from Nikon Instruments Inc. enables superresolution imaging of live cells at 10× the speed of conventional SIM. High-speed imaging is provided at 0.067 s/frame. The illumination system enables imaging at rates of 15 fps. The N-SIM S streamlines workflows and improves operating efficiency by automatically switching between observation methods and...
Nikon Instruments Inc.
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Silica Fiber Custom Ball Lens Profiles
Laser Components can now provide custom ball lens profiles on the end faces of silica fibers. The plasma-based CMS process with ring-of-fire technology supports fiber diameters of 200, 365,...
Laser Components USA Inc.
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Surface-Mount LEDs
The LSM0603 series of surface-mount (SMD) LEDs from Visual Communications Co. provide a small footprint of 1.6 × 0.8 × 0.55 mm. OEMs can choose from SMD chip LEDs in red, white,...
VCC (Visual Communications Co.)
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Spectroscopy Measurement Software
The EasyTau 2 software package from PicoQuant GmbH combines fully automated fluorescence spectra measurement with powerful, easy-to-use data analysis for a fully integrated, comprehensive suite of...
PicoQuant GmbH
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Silicon CCD High-Resolution Camera
MKS Instruments Inc. has announced the Ophir SP920G GigE Silicon CCD High-Resolution Camera designed specifically for industrial laser beam profiling applications. The camera accurately...
MKS Instruments Inc.
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Tunable VCSEL Platform
A novel Tunable Vertical Cavity Surface Emitting Laser (Tunable VCSEL) platform for OCT imaging applications has been announced by Axsun Technologies Inc. The platform leverages...
Excelitas Technologies Corp.
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Scientific CMOS Camera
The pco.panda 4.2 bi camera from PCO AG is a back-illuminated (bi) scientific CMOS camera in an ultracompact housing. The front of the sensor holds the CMOS circuitry. Because this circuitry...
PCO-TECH Inc.
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Laser Scanning Microscopes
The ZEISS LSM 8 laser scanning microscopy family from Zeiss now features the Airyscan area detector. The 32-channel GaAsP array detector captures more spatial information than traditional...
Carl Zeiss Microscopy GmbH, Microscopy
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Large-Format CCD Cameras
The deep-cooled, ultralarge-format SOPHIA 4096B cameras from Princeton Instruments Inc. are engineered for applications ranging from astronomy to fluorescence imaging. The back-illuminated CCD...
Teledyne Princeton Instruments
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Test Targets
The Newport Super High Resolution USAF test targets from MKS Instruments Inc. are designed for high-resolution microscope systems. The targets are mounted in a black-anodized aluminum...
MKS Instruments Inc.
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Microscope Eyepieces
Microscope Eyepieces from Edmund Optics Inc., sold separately for convenience, attach to a wide variety of microscope systems. The eyepieces feature designs made up of an achromatic doublet and...
Edmund Optics
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