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BioPhotonics - February 2007
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Issue Library
Features
Probes Light the Way for Advances in FRET
First described almost 60 years ago, Förster resonance energy transfer (FRET) traditionally uses two molecules — donor and acceptor — to visualize biological activity. Today the technique continues...
Ultrafast, Ultrawide-Band Spectroscopy
The interdisciplinary study of molecular science aims to expand our knowledge of everything around us, from the molecular bonds that give plastic widgets their strength to the electron transitions...
As We Go To Press
Imaging reveals intracranial bleeding in asymptomatic newborns
A recent neonatal brain development study led by Dr. John H. Gilmore of the University of North Carolina School of Medicine at Chapel Hill used MRI to assess intracranial hemorrhage in 88 babies...
Flaws discovered in oncology microarray studies
Scientists generally classify microarray analysis as a type of discovery-based research. As with hypothesis-based procedures, such research must incorporate sound principles of statistical analysis...
An ultrasensitive and ultraselective uranium sensor
Uranium poses a threat to human health and the environment, but the most sensitive methods of uranium detection require costly and bulky laboratory instruments. Therefore, keen analysis currently...
Gadolinium-based MRI contrast agents and a rare condition
Research has revealed an association between the commonly used gadolinium-based MRI contrast agents and a rare disease called nephrogenic systemic fibrosis. The vast majority of the cases have...
BreakthroughMedia
Confocal microscopy
The Atlas of Confocal Laser Scanning In-Vivo Microscopy in Ophthalmology discusses the principles of confocal in vivo microscopy, including slit-scanning techniques, the basics of image formation and...
Live-cell imaging
Two protocols for visualizing live cells are accessible in the January issue (Volume 2, Issue 1) of the online database Cold Spring Harbor Protocols, produced by Cold Spring Harbor Laboratory Press...
Bionanotechnology
The 298-page volume Biomolecular Computation for Bionanotechnology details the tools, methods and issues that are driving research in nonsilicon computing technology. It discusses the process of...
Laser safety
The “2007 Laser Safety Training Catalog” from Laser Institute of America provides an overview of the organization’s local and online course offerings. Available in print and in pdf, the 18-page...
Research products
The “2007 Life Science Catalog” from Promega Corp. details items for amplification, genetic identity, microarray analysis, in vitro transcription, molecular diagnostics, DNA and RNA purification,...
Labels, conjugates
Available from Evident Technologies Inc., the “Life Sciences Catalog V9” details quantum dot fluorescent labels and conjugates for research in the life sciences. The first part of the 24-page...
Laboratory guide
An addition to the Experimenter Series, the fourth edition of Molecular Biology and Genomics includes sections on minisequencing, pyrosequencing and RNA-interference, as well as a brief introduction...
Assay technology
The second edition of the report “Assay Development and Technologies” from Research and Markets Ltd. provides an assessment of the capabilities, strengths, weaknesses and expectations of assays and...
Multidetector CT
The volume Atlas of Non-Invasive Coronary Angiography by Multidetector Computed Tomography presents more than 160 illustrations — 116 of them in color — depicting the capacity of the technique to...
IR fluorescent reagents
The “Infrared Fluorescent Products and Applications Guide” from Li-Cor Biosciences presents an expansion of reagent products, including the IRDye infrared dye secondary antibodies and conjugates,...
Postscripts
Close observation reveals unexpected player in coral reef recovery
Coral reefs comprise arguably some of the most diverse, fragile and beautiful ecosystems on the planet. Their structure, composed mainly of calcium carbonate secreted by living coral polyps, provides shelter for fish and marine invertebrates and helps protect nearby shorelines from erosion. Their critical role, however, cannot save them from destruction — other less hospitable ecosystems are...
Products
Filter sets
With the addition of 15 filter sets for as many fluorescent proteins, Omega Optical Inc. now offers filter sets for a total of 35 proteins. Providing a high signal-to-noise ratio for low-light-level live-cell imaging experiments, the sets are manufactured using the proprietary Alpha technology, which produces steep slopes and accurate band placement for maximizing excitation and emission energy....
Omega Optical LLC
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DPSS lasers
Cobolt AB has released higher-power models of its Cobolt Calypso CW diode-pumped solid-state lasers. They are suitable for applications including cell sorting, high-throughput bioanalysis, and...
Cobolt AB
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Fluorescence filters
JDSU now provides custom fluorescence filters for biomedical applications such as fluorescence microscopy, flow cytometry, microarray scanning, microplate reading, high-content screening and...
Lumentum Operations LLC
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Confocal Raman microscopy
Princeton Instruments/Acton has launched its TriVista confocal Raman microscopy system. The triple spectrograph detects minute structural changes with resolution up to 0.13 cm–1 and low-frequency...
Teledyne Princeton Instruments
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Imaging software
Siemens Medical Solutions Inc. has updated its Radiology Information System software with the introduction of syngo Workflow 28.0 SLR. The medical imaging software is designed as an easy-to-learn...
Siemens Medical Solutions USA Inc.
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Laser diodes
Edmund Optics Inc. has introduced a line of laser diode modules for OEMs to integrate into medical or research equipment. The 10 models are modulated or unmodulated, have 635- or 785-nm beams,...
Edmund Optics Inc.
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UV spectrometer
McPherson Inc. has released the 248/310, an ultraviolet and soft x-ray spectrometer. The instrument can detect wavelengths from ~1 to 300 nm and can measure laser harmonics from 4 eV to 1.2 keV. It...
McPHERSON
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Mass spectrometry
Fleximaging 2.0 software from Bruker Daltonics Inc. enables acquisition and evaluation of Maldi-Tof and Tof/Tof data with its Flex mass spectrometers. Maldi imaging with the software enables...
Bruker Daltonics Inc.
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Small monitor
The UNO from Gentec Electro-Optics Inc. is a power monitor that reads both thermal- and photodetectors. It has a 76 × 57-mm LCD display with 23-mm digits that are high in contrast, allowing them to...
Gentec Electro-Optics Inc.
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Streak camera
The OptoScope SC Streak Camera from Optronis GmbH provides time-resolution measurements from milliseconds down to 2 ps. It features a 100-MHz Ethernet interface, synchroscan mode operation up to 250...
Optronis GmbH
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USB 2.0 cameras
Measuring 44 × 44 × 56 mm, the Lm series CCD cameras are suitable for industrial and scientific applications involving space constraints and low-light conditions. Available from Lumenera Corp., they...
Teledyne Lumenera
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700-MB/s frame grabber
Epix Inc. has released Pixci E4, a frame grabber for use with four-lane PCI Express buses. Featuring an advanced chip that has high-speed serial transceivers, made by Altera Corp., the card can...
EPIX Inc.
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LED light sources
The Dragon series high-power LED light sources from Lightspeed Technologies provide narrow- or broadband output in a wide-field or focused beam. The flexible system of interchangeable components...
Lightspeed Technologies Inc.
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Fiber light source
Intensilight, a mercury-fiber light source, never requires alignment and provides stable, flicker-free illumination for epifluorescence research. Produced by Nikon Instruments Inc., the device has a...
Nikon Instruments Inc.
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Filter wheel
For optical microscopes, Tofra Inc. has released a filter wheel with an integrated controller that saves space. The wheel is compact, measuring 17 mm thick with a maximum package dimension of 180 mm....
Tofra Inc.
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Lifetime measurement
PicoQuant has introduced the PHR 800, a router that enables connection of up to four PicoHarp photon-counting systems. With the interconnected systems, users can simultaneously measure fluorescence...
PicoQuant GmbH
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Diode laser
Alfalight Inc. has introduced a diode laser that provides 6 W of 976 ±4-nm output into a 105-μm, 0.15-numerical-aperture fiber. Its compact, hermetic six-pin package meets the Telcordia GR-468...
Alfalight Inc.
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Deformable mirror
An enhanced deformable mirror from Boston Micromachines Corp. improves the performance of retinal imaging systems, enabling earlier detection of eye diseases such as glaucoma, diabetic retinopathy...
Boston Micromachines Corp.
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Optical trap detectors
Large-aperture, multireflection optical trap detectors are available from Spectrum Detector Inc. Based on National Institute of Standards and Technology traceable calibration-transfer standards, the...
Gentec-EO USA Inc.
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Near-IR Camera
XenICs has introduced the Cheetah near-IR digital camera, which is available in models that have frame rates of 60, 400 or 1750 Hz. Utilizing an InGaAs detector that provides 640 × 512-pixel...
Xenics
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Diode lasers
A line of high-brightness, single-emitter diode lasers in the 650- to 690-nm range has been announced by nLight Corp. The devices rely on proprietary nXLT technology and are available in either...
nLIGHT Inc.
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